Sona Nanotech Inc. (CSE: SONA) (OTCQB: SNANF) (the ‘Company’, ‘Sona’) is pleased to announce that its Chief Scientific Officer, Dr. Len Pagliaro, has been invited to showcase Sona’s developing Targeted Hyperthermia Therapy (‘THT’) cancer treatment today at the Nanotechnology Characterization Laboratory (‘NCL’). Sona will be one of six commercial and academic collaborators to present its research at the NCL’s 20th anniversary ‘Advancing Medical Applications of Cancer Nanotechnology’ symposium. Sona’s subsidiary was previously selected for the NCL Assay Cascade Program, the premier program in the World for bringing nanomaterials through critical preclinical stages and facilitating regulatory review, in which Sona’s materials were assessed for biocompatibility. The NCL was established by the National Cancer Institute (‘NCI’) to accelerate the progress of nanomedicine by providing preclinical characterization and safety testing of nanoparticles. The NCL is a collaborative effort between NCI, the U.S. Food and Drug Administration (‘FDA’), and the National Institute of Standards and Technology.

The Company is also pleased to provide an update on the status of its current operating activities, notably the development of its Targeted Hyperthermia Therapy which uses the Company’s patented, biocompatible gold nanorods (‘GNRs’) to act as an immune stimulator for the treatment of certain solid cancers.

In addition to closing an over-subscribed $3.1 million equity financing in September, the Company has completed pilot safety and biocompatibility feasibility studies conducted by a global contract research organization (‘CRO’) and a preclinical, GLP-compliant translational research institute, respectively, in the United States. Both preclinical studies provided initial data which determine that the Company’s proprietary and uniquely biocompatible GNRs are non-toxic, safe and the GNRs clear the body efficiently. Based on the success of these two studies, the Company has commissioned a full dose-escalation study which is required to inform and support the study protocol for a first-in-human early feasibility study (‘EFS’) being pursued by the Company. The Company will provide updates as to the status of its progress towards an EFS study as significant milestones are achieved.

Also, the previously announced results from the Company’s melanoma and triple negative breast cancer pre-clinical studies have now been submitted for peer review and consideration for publishing in a scientific journal. The working title for the paper, ‘Targeted Intra-tumoral Hyperthermia using Sona Nanotech’s Uniquely Biocompatible Gold Nanorods Induces a Strong Immunogenic Cell Death Response in Two Immunogenically ‘Cold’ Tumor Models‘ highlights the unique mechanism of action of our novel immunotherapy. Work on a pre-clinical study of THT for a colorectal cancer model continues at Dalhousie University with results expected later in November.

Sona Nanotech CEO, David Regan commented, ‘Sona’s preclinical efficacy data for its THT is encouraging in its ability to modify cancers and activate an immune response that significantly reduces not only treated tumors but also untreated metastases. These promising data compel us to pursue an aggressive path towards securing approvals to treat those suffering from late-stage solid cancers that have been unresponsive to current treatment regimens. With supportive initial preclinical safety data from world class CRO partners now in-hand, Sona is pursuing an early feasibility study to assess THT’s safety and efficacy in humans in 2025.‘

About Sona Nanotech Inc.

Sona Nanotech, a nanotechnology life sciences company, is developing Targeted Hyperthermia, a photothermal cancer therapy, which uses therapeutic heat to treat solid cancer tumors. The heat is delivered to tumors by infrared light that is absorbed by Sona’s gold nanorods in the tumor and re-emitted as heat. Therapeutic heat (42-48°C) stimulates the immune system, shrinks tumors, inactivates cancer stem cells, and increases tumor perfusion – thus enabling drugs to reach all tumor compartments more effectively. The size, shape, and surface chemistry of the nanorods target the leaky vasculature of solid tumors, and the selective thermal sensitivity of tumor tissue enables the therapy to deliver clean margins. Targeted Hyperthermia promises to be safe, effective, minimally invasive, competitive in cost, and a valuable adjunct to drug therapy and other cancer treatments.

Sona has developed multiple proprietary methods for the manufacture of gold nanoparticles which it uses for the development of both cancer therapies and diagnostic testing platforms. Sona Nanotech’s gold nanorod particles are cetyltrimethylammonium (‘CTAB’) free, eliminating the toxicity risks associated with the use of other gold nanorod technologies in medical applications. It is expected that Sona’s gold nanotechnologies may be adapted for use in applications, as a safe and effective delivery system for multiple medical treatments, subject to the approval of various regulatory boards, including Health Canada and the FDA.

CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING INFORMATION: This press release includes certain ‘forward-looking statements’ under applicable Canadian securities legislation, including statements regarding the anticipated applications and potential opportunities of Targeted Hyperthermia Therapy, Sona’s preclinical and clinical study plans, future patent filings and its product development plans. Forward-looking statements are necessarily based upon a number of assumptions or estimates that, while considered reasonable, are subject to known and unknown risks, uncertainties, and other factors which may cause the actual results and future events to differ materially from those expressed or implied by such forward-looking statements, including the risk that Sona may not be able to successfully obtain sufficient clinical and other data to submit regulatory submissions, raise sufficient additional capital, secure patents or develop the envisioned therapy, and the risk that THT may not prove to have the benefits currently anticipated. There can be no assurance that such statements will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements. Accordingly, readers should not place undue reliance on forward-looking statements. Sona disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

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Skyharbour Resources Ltd. (TSX-V: SYH ) (OTCQX: SYHBF ) (Frankfurt: SC1P ) (the ‘Company’) is pleased to announce the commencement of its fall diamond drilling program at the 73,294 hectare Russell Lake Uranium Project (‘Russell’ or the ‘Project’). The Project is 51% owned by Skyharbour as operator with joint-venture partner Rio Tinto Exploration Canada Inc. (‘RTEC’) owning the other 49%. It is strategically located in the central core of the Eastern Athabasca Basin of northern Saskatchewan with access to regional infrastructure including an all-weather road and powerline. Skyharbour is planning a 4,500-metre diamond drilling program in seven to nine holes at the project, building on the successful results from the drilling campaign completed earlier this year. The Company’s geologists, along with a contracted drilling crew, are based at Skyharbour’s exploration camp on the McArthur River-Key Lake haul road, situated within five kilometres of Denison Mines’ Phoenix deposit at the Wheeler River Project.

Russell Lake Project Location Map:

http://www.skyharbourltd.com/_resources/images/SKY-RussellLake-20220325-Inset.jpg

Fall Diamond Drilling Program at Russell Lake:

Skyharbour plans to complete approximately 4,500 metres of drilling at Russell to follow up on notable previous exploration and findings and to test new targets developed by the geological team . The drilling program will be focused on the road-accessible Fork target within the broader Grayling target area as well as the M-Zone Extension (‘MZE’) target. All-in drilling costs are lower given the nearby infrastructure including the mine and mill haul road as well as Skyharbour’s exploration camp at the project. A total of 4,500 metres in seven to nine holes is planned with five to six holes planned on the Fork target and two to three holes planned on the MZE target.

Russell Lake Project Target Areas:

https://www.skyharbourltd.com/_resources/images/20240110-MainTargetsRussellLake2024.jpg

The Fork target is a newly identified target to the west of the Grayling Zone and on-strike with Denison’s M-Zone at their adjacent Wheeler River Project. Earlier this year, the best intercept of uranium mineralization historically on the Russell Lake Project was discovered in hole RSL24-02, which returned a 2.5 metre wide intercept of 0.721% U ₃ O ₈ at a relatively shallow depth of 338.1 metres, including 2.99% U ₃ O ₈ over 0.5 metres just above the unconformity in the sandstone (see news release dated July 19 ^th , 2024, titled: ‘Skyharbour Drills New Discovery at Russell Project with High-Grade Uranium Mineralization Up to 3.0% U ₃ O ₈ at Newly Identified Fork Zone’). This high-grade intercept is a new discovery at the recently identified Fork Target which has very limited historical exploration due to a lack of reliable geophysical data and drill targets resulting from nearby powerline interference. The mineralization is open in most directions including along strike, and will be a focus for this drill program.

Fork and Grayling Drill Targets:

https://www.skyharbourltd.com/_resources/images/20240110-ForkGraylingEastTargetsRussellLake.jpg

Skyharbour has also refined additional drill targets in the M-Zone Extension area, along trend from the Grayling Zone and Denison’s M-Zone, where historical drilling intersected basement-hosted uranium. More recent drilling by Denison in 2020 at the M-Zone encountered uranium mineralization with significant faulting, core loss, geochemical anomalies, and radioactivity encountered in other drill holes. Like the Grayling Zone, the mineralization is hosted by a graphitic thrust fault within a significant magnetic low. It is also noted that cross structures associated with Denison’s Phoenix and Gryphon uranium deposits potentially trend onto the Russell Lake property within the M-Zone Extension target area, further enhancing the prospectivity of this target.

M-Zone Extension Drill Targets:

https://www.skyharbourltd.com/_resources/images/20240110-M-ZoneExtensionTargetsRussellLake.jpg

Russell Lake Project Historical Summary:

The Russell Lake Project is a large, advanced-stage uranium exploration property totalling 73,294 hectares strategically located between Cameco’s Key Lake and McArthur River Projects and adjoining Denison’s Wheeler River Project to the west and Skyharbour’s Moore Uranium Project to the east. The northern extension of Highway 914 between Key Lake and McArthur River runs through the western extent of the Property and greatly enhances accessibility, while a high-voltage powerline is situated alongside this road and the western edge of the property south of Key Lake. Skyharbour’s acquisition of Russell Lake creates a large, nearly contiguous block of highly prospective uranium claims totalling 108,999 hectares between the Russell Lake and the Moore uranium projects.

There has been historical exploration carried out at Russell Lake. However, most of it was conducted before 2010, prior to the discovery of several major deposits in and around the Athabasca Basin. In 2023, Skyharbour’s inaugural diamond drilling program tested several Fox Lake Trail targets and the Grayling Zone. Significant uranium mineralization was intersected in the majority of holes at the Grayling Zone over a strike length exceeding one kilometre. More recently, Skyharbour completed 5,152 metres of drilling in a 2024 winter/spring drill program making a new discovery at the newly identified Fork Target area. Hole RSL24-02 marks the best intercept of uranium mineralization historically at the project, returning a 2.5 metre wide intercept of 0.721% U ₃ O ₈ at a relatively shallow depth of 338.1 metres, including 2.99% U ₃ O ₈ over 0.5 metres at 339.6 metres just above the unconformity in the sandstone.

2024 Fork Target Drill Hole Location Map:

https://www.skyharbourltd.com/_resources/maps/2024-Fork-East-Grayling-Drill-Hole-Location-Map-NR-new-002.jpg

Several notable exploration targets exist on the property including the Grayling Zone, the M-Zone Extension target, the Little Man Lake target, the Christie Lake target, the Fox Lake Trail target and the newly identified Fork Zone target. More than 35 kilometres of largely untested prospective conductors in areas of low magnetic intensity also exist on the Property.

Qualified Person:

The technical information in this news release has been prepared in accordance with the Canadian regulatory requirements set out in National Instrument 43-101 and reviewed and approved by David Billard, P.Geo., a Consulting Geologist for Skyharbour as well as a Qualified Person. Mr. Billard has verified the data disclosed, which includes a review of the sampling, analytical and test data underlying the information and opinions contained herein.

About Skyharbour Resources Ltd.:

Skyharbour holds an extensive portfolio of uranium exploration projects in Canada’s Athabasca Basin and is well positioned to benefit from improving uranium market fundamentals with interest in twenty-nine projects, ten of which are drill-ready, covering over 580,000 hectares (over 1.4 million acres) of land. Skyharbour has acquired from Denison Mines, a large strategic shareholder of the Company, a 100% interest in the Moore Uranium Project, which is located 15 kilometres east of Denison’s Wheeler River project and 39 kilometres south of Cameco’s McArthur River uranium mine. Moore is an advanced-stage uranium exploration property with high-grade uranium mineralization at the Maverick Zone that returned drill results of up to 6.0% U ₃ O ₈ over 5.9 metres, including 20.8% U ₃ O ₈ over 1.5 metres at a vertical depth of 265 metres (see news release dated February 27 ^th , 2017, titled: ‘Skyharbour Intersects 20.8% U ₃ O ₈ over 1.5 Metres in First Drill Hole at Maverick Zone and Discovers New High-Grade Uranium Lens on Moore Lake Uranium Project’). Adjacent to the Moore Project is the Russell Lake Uranium Project, in which Skyharbour is an operator with joint-venture partner RTEC. The project hosts several high-grade uranium drill intercepts over a large property area with robust exploration upside potential. The Company is actively advancing these projects through exploration and drill programs.

Skyharbour also has joint ventures with industry leader Orano Canada Inc., Azincourt Energy, and Thunderbird Resources (previously Valor) at the Preston, East Preston, and Hook Lake Projects respectively. The Company also has several active earn-in option partners, including CSE-listed Basin Uranium Corp. at the Mann Lake Uranium Project; CSE-listed Medaro Mining Corp. at the Yurchison Project; TSX-V listed North Shore Uranium at the Falcon Project; UraEx Resources at the South Dufferin and Bolt Projects; Hatchet Uranium at the Highway Project and TSX-V listed Terra Clean Energy (previously Tisdale) at the South Falcon East Project which hosts the Fraser Lakes Zone B uranium and thorium deposit. In aggregate, Skyharbour has now signed earn-in option agreements with partners that total over $40 million in partner-funded exploration expenditures, over $30 million worth of shares being issued, and over $22 million in cash payments coming into Skyharbour, assuming that these partner companies complete their entire earn-ins at the respective projects.

Skyharbour’s goal is to maximize shareholder value through new mineral discoveries, committed long-term partnerships, and the advancement of exploration projects in geopolitically favourable jurisdictions.

Skyharbour’s Uranium Project Map in the Athabasca Basin:

https://www.skyharbourltd.com/_resources/images/SKY_SaskProject_Locator_2024-02-14_V2.jpg

To find out more about Skyharbour Resources Ltd. (TSX-V: SYH) visit the Company’s website at www.skyharbourltd.com .

Skyharbour Resources Ltd.

‘Jordan Trimble’
________________________________________
Jordan Trimble

President and CEO
For further information contact myself or:
Nicholas Coltura
Investor Relations Manager
‎Skyharbour Resources Ltd.
‎Telephone: 604-558-5847
‎Toll Free: 800-567-8181
‎Facsimile: 604-687-3119
‎Email: info@skyharbourltd.com

NEITHER THE TSX VENTURE EXCHANGE NOR ITS REGULATION SERVICES PROVIDER ACCEPTS RESPONSIBILITY FOR THE ADEQUACY OR ACCURACY OF THE CONTENT OF THIS NEWS RELEASE.

Forward-Looking Information

This news release contains ‘forward‐looking information or statements’ within the meaning of applicable securities laws, which may include, without limitation, completing ongoing and planned work on its projects including drilling and the expected timing of such work programs, other statements relating to the technical, financial and business prospects of the Company, its projects and other matters. All statements in this news release, other than statements of historical facts, that address events or developments that the Company expects to occur, are forward-looking statements. Although the Company believes the expectations expressed in such forward-looking statements are based on reasonable assumptions, such statements are not guarantees of future performance and actual results may differ materially from those in the forward-looking statements. Such statements and information are based on numerous assumptions regarding present and future business strategies and the environment in which the Company will operate in the future, including the price of uranium, the ability to achieve its goals, that general business and economic conditions will not change in a material adverse manner, that financing will be available if and when needed and on reasonable terms. Such forward-looking information reflects the Company’s views with respect to future events and is subject to risks, uncertainties and assumptions, including the risks and uncertainties relating to the interpretation of exploration results, risks related to the inherent uncertainty of exploration and cost estimates and the potential for unexpected costs and expenses, and those filed under the Company’s profile on SEDAR+ at www.sedarplus.ca. Factors that could cause actual results to differ materially from those in forward looking statements include, but are not limited to, continued availability of capital and financing and general economic, market or business conditions, adverse weather or climate conditions, failure to obtain or maintain all necessary government permits, approvals and authorizations, failure to obtain or maintain community acceptance (including First Nations), decrease in the price of uranium and other metals, increase in costs, litigation, and failure of counterparties to perform their contractual obligations. The Company does not undertake to update forward‐looking statements or forward‐looking information, except as required by law.

Brunswick Exploration Inc. (TSX-V: BRW, OTCQB: BRWXF; FRANKFURT:1XQ; ‘ BRW ‘ or the ‘ Company ‘) is excited to announce that, following the recent discovery of spodumene near Nuuk, Greenland, it has applied for additional licenses in the Nuuk area. The Company has also increased its holdings in new regions of Western Greenland subsequent to further compilation work including the Disko Bay and Uummannaq areas.

Mr. Killian Charles, President and CEO of BRW, commented: ‘With the lithium potential of Greenland newly confirmed, we have rapidly consolidated all high priority targets in western Greenland. BRW now controls one of the most significant grassroot exploration portfolios in Greenland and is the only company actively exploring for lithium in the country. Our new holdings all benefit from proximity to communities and tidal water to ensure that logistical and infrastructure needs are in place for potential future development. Between our new Ivisaartoq discovery and our expanded portfolio, we look forward to launching a major lithium exploration initiative in 2025 across Greenland as soon as possible. We are very keen to work with the Greenlandic communities, government and European Commission as we launch this exciting endeavor.’

Figure 1: BRW Lithium Portfolio

‘With several discoveries across its expanding portfolio, BRW will continue to leverage its lithium expertise to generate and advance targets to the benefit of its shareholders. With continuous drilling success at Mirage, the potential for new discoveries at Anatacau West and the start of a significant exploration campaign in Greenland, BRW is well positioned to deliver exciting results throughout 2025.’

All new license areas have been applied for and are pending final government approval. They were staked based on favorable geological environments and satellite imagery. Greenland has exceptional outcrop exposure and BRW’s 2024 discovery showcases significant lithium potential for the country. In total, BRW acquired 92,547 hectares of new license area that contains hundreds of mapped and interpreted pegmatites of which 90 are between 500 and 2,000 meters in length. None of the new areas staked by BRW have been previously explored for lithium.

Brunswick Exploration would like to thank Xploration Services Greenland A/S for their assistance in the applications as well as other project aspects during the 2024 season.

Nuuk Expansion

The Nuuk holdings host the new Ivisaartoq discovery within the Ivisaartoq belt (see press release October 30 ^th ). The Company has applied to stake the adjacent Ujarassuit amphibolite belt that is up to 1 kilometer in width and roughly 40 kilometers in strike length. In addition, the company has staked additional amphibolite belts within the Fiskefjord Complex, 95 kilometers north of Nuuk, and 75 kilometers southeast of the community of Maniitsoq. These belts are up to 4.5 kilometers in width and 20 kilometers in strike length. In total, the new claims contain hundreds of mapped and interpreted pegmatite outcrops including 6 that are between 500 and 2,000 meters in strike length for a total license expansion area of 33,138 hectares. (See Figure 2).

Figure 2: Newly Expanded Nuuk License

Disko Bay

The Disko Bay licenses are located roughly 30-80 kilometers from the coastal city of Ilulissat, which is the 3 ^rd largest city in Greenland. The licenses are near multiple seaports and container terminals, including Ilulissat, which has a population of over 4,500 people. The area is situated within the Aasiaat domain, part of the Paleoproterozoic Nagssugtoqidian Orogen, sandwiched to the south by the Archean North Atlantic Craton and to the North by the Archean Rae Craton. The Orogen extends west into the Trans-Hudson orogeny of Canada that continues to the lithium deposits near Snow Lake Manitoba and the Black Hills of South Dakota.

Multiple amphibolite and metasedimentary belts were acquired with some belts being over 20 kilometers in strike length. The new claims have hundreds of mapped and interpreted pegmatite targets including 54 that are between 500 and 2,000 meters in strike length for a total license area of 49,639 hectares.

Figure 3: Disko Bay License Overview

Uummannaq

The licenses are located roughly 70 kilometers from the coastal city of Uummannaq, which is roughly 80 kilometers north of Ilulissat. Uummannaq has a population of roughly 1,660, an airport and a ferry terminal as well as a nearby container terminal. The area is located within the Archean Rae Craton that is intermixed with the Paleoproterozoic Rinkian fold-thrust belt, both of which are in contact with the Paleoproterozoic Nagssugtoqidian Orogen to the south.

The new license contains multiple amphibolite and metasedimentary belts with dozens of mapped and interpreted pegmatites of which 30 are between 500 and 2,000 meters in strike length with a total license area of 9,770 hectares.

Figure 4: Uummannaq License Overview

Qualified Person

The scientific and technical information related to this press release has been reviewed and approved by Mr. Charles Kodors, Manager Atlantic Canada. He is a Profession Geologist registered in New Brunswick, Nova Scotia, Newfoundland, Quebec, Ontario, Manitoba and Saskatchewan.

About Brunswick Exploration

Brunswick Exploration is a Montreal-based mineral exploration company listed on the TSX-V under symbol BRW. The Company is focused on grassroots exploration for lithium, a critical metal necessary to global decarbonization and energy transition. The company is rapidly advancing its extensive portfolio of lithium projects in Canada and Greenland including the Mirage and the Anatacau Projects and the new Ivisaartoq lithium discovery.

Investor Relations/information

Mr. Killian Charles, President and CEO ( info@BRWexplo.com )

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release

Cautionary Statement on Forward-Looking Information

This news release contains ‘forward-looking information’ within the meaning of applicable Canadian securities legislation based on expectations, estimates and projections as at the date of this news release. Forward-looking information involves risks, uncertainties and other factors that could cause actual events, results, performance, prospects and opportunities to differ materially from those expressed or implied by such forward-looking information. Factors that could cause actual results to differ materially from such forward-looking information include, but are not limited to, delays in obtaining or failures to obtain required governmental, environmental or other project approvals; uncertainties relating to the availability and costs of financing needed in the future; changes in equity markets; inflation; fluctuations in commodity prices; delays in the development of projects; the other risks involved in the mineral exploration and development industry; and those risks set out in the Corporation’s public documents filed on SEDAR at www.sedar.com. Although the Corporation believes that the assumptions and factors used in preparing the forward-looking information in this news release are reasonable, undue reliance should not be placed on such information, which only applies as of the date of this news release, and no assurance can be given that such events will occur in the disclosed time frames or at all. The Corporation disclaims any intention or obligation to update or revise any forward-looking information, whether as a result of new information, future events or otherwise, other than as required by law. Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this news release.

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