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  • Data will support design and planning of first in human clinical trials
  • Preparing for pre-IND meeting with the FDA

InMed Pharmaceuticals Inc. (NASDAQ: INM) (‘InMed’ or the ‘Company’), a pharmaceutical company developing a pipeline of proprietary small-molecule drug candidates for diseases with high unmet medical needs, today announced the successful completion of pharmacokinetic (‘PK’) studies in large animal models for its Alzheimer’s disease candidate INM-901.

This marks the first preclinical study in which the oral formulation of INM-901 was administered in large animals. The results provide additional data in guiding decisions in the design of a human Phase 1 clinical trial program.

Positive PK and Neurological Assessment Results

Over a seven-day dosing period, the studies demonstrated robust bioavailability in in vivo models. INM-901 achieved what is anticipated to be therapeutic levels of systemic exposure, supporting its potential utility in neurodegenerative disorders such as Alzheimer’s disease.

In addition, neurological assessments evaluating general attitude, behavior, and motor function revealed no adverse neural or behavioral effects, reinforcing the compound’s favorable profile and supporting its continued advancement toward first-in-human clinical trials.

In parallel, InMed has completed additional chemistry, manufacturing, and controls (‘CMC’) development to scale the INM-901 manufacturing process in preparation for Investigational New Drug (‘IND’)-enabling studies and regulatory interaction with the Food and Drug Administration (‘FDA’).

Dr. Eric Hsu, Senior Vice President, Preclinical Research and Development at InMed, commented, ‘The successful completion of our first large animal PK study is very encouraging for the INM-901 program. The data supports the clinical applicability of our INM-901 oral formulation and provides important insights as we plan and design our IND-enabling studies and Phase 1 clinical trials. Furthermore, the neurological assessments strengthen our confidence in the compound’s overall safety profile.’

Next development steps:

  • Advancing CMC activities for scale-up and supply
  • Dose ranging studies in two species
  • Preparing for a pre-IND meeting with the FDA
  • GLP-enabling studies to support an IND submission

To learn more about the INM-901program, please visit the website at: https://www.inmedpharma.com/pharmaceutical/inm-901-for-alzheimers-disease/.

About InMed:

InMed Pharmaceuticals is a pharmaceutical drug development company focused on developing a pipeline of proprietary small molecule drug candidates targeting the CB1/CB2 receptors. InMed’s pipeline consists of three separate programs in the treatment of Alzheimer’s, ocular and dermatological indications. For more information, visit www.inmedpharma.com.

Investor Contact:
Colin Clancy
Vice President, Investor Relations
and Corporate Communications
T: +1.604.416.0999
E: ir@inmedpharma.com

Cautionary Note Regarding Forward-Looking Information:

This news release contains ‘forward-looking information’ and ‘forward-looking statements’ (collectively, ‘forward-looking information’) within the meaning of applicable securities laws. Forward-looking statements are frequently, but not always, identified by words such as ‘expects’, ‘anticipates’, ‘believes’, ‘intends’, ‘potential’, ‘possible’, ‘would’ and similar expressions. Such statements, based as they are on current expectations of management, inherently involve numerous risks, uncertainties and assumptions, known and unknown, many of which are beyond our control. Forward-looking information is based on management’s current expectations and beliefs and is subject to a number of risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. Without limiting the foregoing, forward-looking information in this news release includes, but is not limited to, statements about: the efficacy of INM-901; the favorable bioavailability profile of INM-901 oral formulation; planning and preparation for pre-IND meeting with the FDA; positive results demonstrating robust bioavailability of INM-901; no adverse neural or behavioral effects using INM-901; the clinical applicability of our INM-901 oral formulation; INM-901’s overall safety profile and next development steps including advancing CMC, dose ranging and GLP studies.

Additionally, there are known and unknown risk factors which could cause InMed’s actual results, performance, or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking information contained herein. A complete discussion of the risks and uncertainties facing InMed’s stand-alone business is disclosed in InMed’s Annual Report on Form 10-K and other filings with the Securities and Exchange Commission on www.sec.gov.

All forward-looking information herein is qualified in its entirety by this cautionary statement, and InMed disclaims any obligation to revise or update any such forward-looking information or to publicly announce the result of any revisions to any of the forward-looking information contained herein to reflect future results, events or developments, except as required by law.

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To view the source version of this press release, please visit https://www.newsfilecorp.com/release/274918

News Provided by Newsfile via QuoteMedia

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The House Freedom Caucus is rallying behind one of its own members’ push to impeach U.S. District Judge James Boasberg.

Rep. Brandon Gill, R-Texas, introduced an impeachment resolution against Boasberg last month for his role in Arctic Frost, a code name for ex-special counsel Jack Smith’s probe into President Donald Trump and the 2020 election.

Gill argued Boasberg acted in a partisan fashion when he signed off on subpoenas and gag orders related to the investigation, including subpoenas for phone records from several Republican legislators in Congress — the news of which was made public in documents released by Senate Judiciary Committee Chairman Chuck Grassley, R-Iowa, this year.

But it’s not immediately clear whether the push to impeach Boasberg is strong enough to launch an actual pressure campaign on House GOP leaders.

‘It absolutely should be done,’ House Freedom Caucus Chairman Andy Harris, R-Md., told Fox News Digital last week. ‘I think this is levels above what we thought was going on. His bias is pretty clear, someone with that kind of bias cannot exist in the federal judiciary.’

But Harris signaled it would not be an issue the conservative group would pressure House Speaker Mike Johnson, R-La., on anytime soon.

‘No, we have other issues as well. We’re concentrated right now on the fiscal issues,’ Harris said when asked if he would bring the issue to House leaders. ‘But we have discussed that, and there is broad support to impeach the judge.’

Still, his conservative caucus appears largely supportive.

‘I think there’s considerable movement over here, particularly in light of, actually the genesis here, Arctic Frost … the massive concerns we have with what the judge is doing — just making up facts out of thin air and assumptions based on motives that have no basis,’ House Freedom Caucus Policy Chairman Chip Roy, R-Texas, told Fox News Digital.

Rep. Ralph Norman, R-S.C., who is also running for governor of South Carolina, told Fox News Digital, ‘I hope so,’ when asked if this impeachment push would be stronger than the last.

‘He’s so partisan. He’s one of the rogue judges that exist today,’ Norman said. ‘There are consequences for what he did.’

Meanwhile, Rep. Eli Crane, R-Ariz., pointed out that he was one of the earliest supporters of impeaching judges who conservatives saw as casting overly partisan rulings in the Trump era.

‘I think a lot of these judges have gone way out of bounds and violated their oaths. I’m in support of it, yeah,’ he told Fox News Digital.

He was more cautious when asked if it would yield results. ‘I don’t tend to have confidence in anything around here until I see action taken. Talk is cheap,’ Crane said.

Gill was one of several House Freedom Caucus members to introduce impeachment resolutions against Boasberg this past spring, when he issued an order temporarily blocking Trump’s deportation flights to El Salvador. 

At the time, however, Johnson warned Republicans that impeachment was not the most practical way to curb ‘rogue judges’ — pointing out that removal would require support in the Senate that simply was not there.

Instead, House GOP leaders rallied around a bill by Rep. Darrell Issa, R-Calif., subcommittee chair of the House Judiciary panel’s subcommittee on courts.

That legislation, aimed at limiting the power of district court judges to issue nationwide injunctions, passed the House in early April but was never taken up in the Senate.

Issa himself cautioned against moving too quickly toward impeachment when asked by Fox News Digital last week.

‘We have a number of rogue judges, and I think before we talk about impeachment, with so many people seeing wrongdoing, both the House and the Senate need to hold appropriate hearings and evaluate just what the proper definition of good behavior is and whether not just one, but multiple judges, may have clearly violated that,’ Issa said. ‘I think that’s the right way to approach it.’

Issa said he was ‘looking at’ holding a hearing on the matter when lawmakers returned to Capitol Hill after Thanksgiving.

Fox News Digital reached out to the U.S. Courts system, which declined to comment for this story.


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America is on the cusp of the biggest power-hungry decade in a generation. Federal forecasters expect record electricity demand in 2025–26, even as oil producers are carefully managing output. Yet the main reason your bill is climbing isn’t just regional differences, it’s rules. A thicket of tariffs on essential hardware, marathon permitting timelines, and clogged grid interconnection queues layer a “policy premium” onto every kilowatt-hour. In a textbook supply-and-demand sense, demand is racing ahead, driven by AI data centers and electrification, while policy squeezes supply. Worse, Washington keeps “choosing” technologies, inviting regulatory capture and raising costs for everyone. If we want the AI era to benefit households instead of draining their wallets, we need neutral, pro-entry rules that let the cheapest reliable electrons win. 

Energy inflation tells the tale. Headline prices are running hotter than the 2 percent target, and the pressure points are concentrated in utilities. Electricity alone is up roughly 5 percent, and utility gas is up close to 12 percent versus a year ago. Average retail electricity prices have jumped nearly 9 percent already this year. The burden isn’t uniform. North Dakotans pay the lower energy costs, around 11.7¢ per kWh with a typical bill near $112, while Hawaiians pay roughly 42.3¢ and a $203 monthly tab. That gulf largely reflects system design and policy. North Dakota sits on abundant generation with strong ties to the Midcontinent grid; Hawaii is an islanded system importing fuel and equipment with layers of costs. When transmission is constrained and hardware is expensive, consumers pay.

Energy demand is taking off, mainly driven by data centers powering AI. Data-center electricity use tripled over the last decade to roughly 176 terawatt-hours, and federal analysts expect it to double, or even triple, again by 2028. That would take data centers from roughly 4.4 percent of US electricity consumption to something like 10–12 percent in just a few years. In markets with heavy data-center clustering, wholesale prices near key nodes have surged, reportedly doubling or tripling compared with five years ago, and those spikes bleed into retail rates. The largest campuses are now measured in hundreds of acres; Meta’s complex in Prineville, Oregon, covers well over a hundred. None of this is a problem if supply can scale. But supply is boxed in. 

Start with trade policy. The grid is steel, copper, aluminum, power electronics, batteries, transformers, inverters, and miles of conductor, exactly the things Washington keeps taxing. Many power-sector inputs now carry duties in the 25–50 percent range. The administration has announced additional tariffs on medium and heavy trucks, which will raise logistics costs across energy supply chains. For oil and gas, the exemption record is mixed: while crude itself may avoid new levies, drillers and midstream firms still buy tariffed inputs — steel casing, line pipe, valves — magnifying project costs. Steel and aluminum duties, recently doubled to 50 percent in some cases, raise the price of everything from rigs to transmission towers. On the “green” side, tariff policy is even more tangled. Grid-scale batteries face total duty stacks approaching the mid-sixties percent; aluminum and derivative products also pay 25 percent. Solar modules and cells still sit under safeguard tariffs near the mid-teens, layered atop other levies. The result is not a level playing field but a politicized one where lobbyists fight to be a “protected” winner and consumers lose either way. 

Then there’s the permitting time tax. Big energy projects routinely wait six or more years for approvals; some major transmission lines have been in limbo for more than a decade. Meanwhile, the grid clogs and aging infrastructure strains. Transmission congestion alone added roughly $11.5 billion to customer bills last year. Lengthy reviews no longer deliver meaningfully cleaner or safer outcomes; they mostly deliver uncertainty, which raises financing costs and deters entrants. In economics, that’s classic deadweight loss. 

Interconnection is the third vice. You can’t sell power until a grid operator studies how your plant will affect the system. For years, independent system operators and regional transmission organizations have been drowning in applications, many of them speculative. Backlogs keep new capacity — renewables, nuclear uprates, even industrial cogeneration — from plugging in. Regulators have introduced helpful reforms: “cluster studies” that analyze groups of projects at once and “readiness screens” to ensure entrants have site control and basic financing before staff spends months modeling them. But adoption is uneven. Markets like the California Independent System Operator are making headway with annual intake cycles and clearer milestones; others are still stuck, creating a patchwork of rules that adds friction and encourages forum shopping. Even good projects die on the vine if siting processes collide with wildlife, historic-preservation, and local zoning rules that were never designed for 21st-century energy density. 

Why do we tolerate all this? Because we keep trying to direct outcomes, favoring particular fuels, geographies, or industrial constituencies, rather than setting simple, technology-neutral rules. That invites regulatory capture. When agencies tilt toward the loudest incumbent or the trendiest technology, they’re not discovering the lowest-cost path to reliability; they’re rationing permits and tax credits. Households and factories pay the markup. 

What would a pro-consumer pro-technology agenda look like? 

First, stop playing favorites. Drop the tariff thicket on intermediate goods central to generation, storage, and transmission. Don’t carve out oil-and-gas inputs but punish solar or vice versa; end the game entirely. Let firms source the cheapest safe equipment globally and let market competition decide the mix of resources. When inputs get cheaper, so do bills. 

Second, rebuild permitting around shot-clocks, not calendars. Establish firm timelines and a single lead agency for major projects; if the clock runs out, move to a decision on the record. Focus intensive reviews on genuinely high-impact projects and allow routine, low-impact work, like reconductoring existing lines or swapping transformers, to proceed quickly under programmatic approvals. Provide judicial review, but time-limit it to curb endless litigation. 

Third, finish the interconnection fix. Make cluster studies and readiness requirements universal, but tune them so they screen out pure speculation without blocking smaller independent power producers. Publish transparent cost-allocation rules so developers can plan. Align interconnection with long-range transmission planning so we’re not endlessly studying plants for a grid that doesn’t exist yet. 

Fourth, open the door to firm, zero-carbon baseload. Small modular reactors and advanced designs, including molten-salt and thorium-based concepts, should compete on their merits. That means modern licensing that evaluates designs by efficiency and productivity, not lineage; standardized approvals for repeat builds; and clarity on waste handling. Clear the obstacles so private capital can try thorium-powered nuclear. If it can deliver reliable power at scale, the market will adopt it. If not, resources will flow elsewhere. Either way, consumers win. 

Finally, remember why we’re doing this. AI is a once-in-a-century general-purpose technology. It can raise productivity and living standards, but only if the power system scales without crippling costs.  

We don’t need another round of picking winners and losers on the energy front. We need to remove the artificial barriers that make supplying power slow and expensive. Cut the policy premium, tariffs that pad equipment costs, permits that drag on for years, interconnection rules that reward queue gaming, and America’s engineers, utilities, and entrepreneurs will do the rest. The cheapest reliable kilowatt-hour is the one that’s allowed to be built.

In recent decades, and especially since the release of OpenAI’s large language model ChatGPT in 2022, artificial intelligence use has rapidly spread into almost every industry. And as AI proliferates, so do fears that a wave of mass unemployment will follow. Concerns are widespread that AI will be deployed to accomplish an ever-greater share of the labor needed throughout the economy, leaving fewer and fewer jobs available for human workers.

This fear led Dario Amodei, one of the world’s leading AI technologists, to sound the alarm earlier this year about an impending “white-collar bloodbath.” The Anthropic CEO told Axios that one very possible scenario within the next one to five years is that, “Cancer is cured, the economy grows at 10 percent a year, the budget is balanced — and 20 percent of people don’t have jobs.”

This was predictably latched onto by economic interventionists, such as US Senator Bernie Sanders. “We must demand that increased worker productivity from AI benefits working people, not just wealthy stockholders on Wall St,” Sanders posted on X in response to Amodei’s statement. Sanders later posted that, “With the explosion of AI, new technology and increased worker productivity, we should demand a shorter work week, increased life expectancy and a decent standard of living for all.” Other politicians have gone even further since then. US Senator Josh Hawley, like Tucker Carlson started advocating years ago, supports banning self-driving cars to protect the jobs of car and truck drivers.

Indeed, AI has already created countless efficiencies and new capabilities throughout the economy that have made specific jobs redundant. Consider the global herbicide industry. A Bloomberg article titled “AI-Powered Weed-Killing Robots Threaten a $37 Billion Market” explains:

After almost a century of deploying a more-is-more approach to chemical herbicides, the global agricultural sector is rapidly rolling out advancements that promise to curb the use of weed-control sprays by as much as 90 percent. Using artificial-intelligence powered cameras, the new sprayers can identify and target invasive plants while avoiding the cash crops. If even a fraction of growers adopt the new tools, it could mean a big shift for crop-chemical majors like Bayer AG and BASF SE.

This potential tenfold improvement in herbicide use efficiency may significantly reduce the agricultural demand for herbicide production, and thus put many people out of their jobs in that industry. And this is just one example. From facilitating new scientific research methods, to transforming solar cell production, to improving healthcare safety, to proliferating self-driving car use, AI offers new ways of doing things throughout every industry, which devalues some skillsets in the job market and rewards others.

However, there is an opposite fear as well. Last month, during a press conference the day he won the 2025 Nobel Prize in economics, Joel Mokyr gave a speech about the grand sweep of economic history. Toward the end of his lecture he weighed in on the AI job loss debate: “As I see it, the main concern about the labor market is not technological unemployment. It’s labor scarcity.”

Mokyr is an economic historian who is renowned for looking at the big picture. And when you do that, it is clear that technological unemployment is nowhere near as big a concern as the set of problems that AI will help solve if politicians like Bernie Sanders and Josh Hawley don’t succeed in debilitating it.

Specific jobs becoming obsolete is only one side of the coin of technology’s effect on employment. The other side of the coin reveals why artificial intelligence will lead to no overall reduction in employment opportunities. Like all prior technological revolutions, AI will create at least as many jobs as it eliminates, and most importantly, the new jobs will tend to be preferable to and easier to find than the old jobs.

Unemployment rates have remained relatively constant and quite low in recent decades, currently standing at about 4.3 percent in the US and 4.9 percent across the globe, according to recent estimates. This is approximately as low as they have ever been.

Meanwhile, ever since the industrial revolution, there has been an explosion of technological advancement and proliferation that has almost completely transformed all economic industries and everyday life across the globe.

Virtually every instance of technological progress reduces the need to employ some specific form of labor. Dish washing machines have meant that homes and restaurants need only employ a small fraction of the cleaning staff that was once required per meal served. Refrigeration has conserved countless labor hours preserving foods. Electric power has exponentiated the manufacturing capability of each factory worker by enabling a new class of machinery. And the list goes on and on.

The constantly low unemployment rate, in light of recent history’s technological progress, would amaze the Industrial-Revolution-era activist group known as the Luddites, a radical labor movement of anti-technologists who rioted and destroyed factory machinery to protect their jobs from automation in the early 19th-century. Their initial concern was for the jobs of craftsmen competing with mechanized looms and knitting equipment that allowed a single worker to produce the output of a hundred craftsmen. But the scope of Luddite animosity quickly widened to oppose industrialization generally.

The nineteenth-century Luddites made the same mistake, known to economists as the “lump of labor fallacy,” that antagonists of AI are making today. In a New York Times article titled “Trump, Immigration and the Lump of Labor Fallacy,” Nobel Prize winning economist Paul Krugman explains the fallacy: “This is the view that there is a fixed amount of work to be done and that if someone or something — some group of workers or some kind of machine — is doing some of that work, that means fewer jobs for everyone else.”

Krugman also explains why this “lump of labor” view is false:

When incomes rise, people will find something to spend their money on, creating jobs for workers displaced by technology or newcomers to the work force. Machines do, in fact, perform many tasks that used to require people; output per worker is more than four times what it was [in 1952], so we could produce 1952’s level of output with only a quarter as many workers. In fact, however, employment has tripled. … No, AI and automation, for all the changes they may bring, won’t ultimately take away jobs, and neither will immigrants.

The point about “incomes rising” is key, because it is a predictable consequence of technological automation and it is also the reason, along with new forms of work created by new technologies, why the newly created jobs will tend to be preferable to the old jobs.

Workers will only be displaced by technology if the technology is capable of producing more valuable output, meaning some net-positive combination of cheaper and higher quality, than human labor. Otherwise, mechanization won’t be profitable and employers will stick to employing humans. Therefore, we can safely bet that wherever AI is displacing human workers, consumers are benefitting from some net-positive combination of falling prices and rising quality. This means that consumers will have more income left to spend, and will therefore consume an ever-wider range of goods and services, thus funding more and more niche forms of employment that replace the jobs lost to technological improvements in the production process.

This is crystal clear if you look at the history of labor specialization. Since the mid 19th century, agriculture has gone from employing about 70 percent of US workers to employing only 2 percent. Meanwhile, the productivity of US agriculture has massively increased due to improved farming technology and food has become about 10 times more affordable for blue-collar workers in the last century.



If no new jobs had been created in America since 1840, this process would have left 68 percent of the population permanently out of work. But to the contrary, the modern economy is composed largely of jobs that people in any prior century probably never even imagined. Web designers, pet therapists, dietitians, travel agents, nail technicians, cosmetic surgeons, neuroscientists, and countless others are employed in now-common forms of labor that would have seemed either laughably frivolous or entirely unimaginable just a century ago. “Really, therapy for my dog while my children are starving?”

For a detailed description of one of the most recent and frivolous new industries imaginable, read the article titled “Does Your Plant Need a Nanny? A new crop of caretakers will spritz, polish and prune your houseplants — and even send photos while you’re away.” published by the New York Times in April. These new “plant nannies” offer virtual plant visits, and services such as speaking to, lighting, and photographing plants while their owners are away, in addition to traditional plant maintenance practices.

New and ever-more-niche and personalized forms of work are constantly made possible by the vast abundance of labor and consumption freed up by labor-saving technology. Monotonous or backbreaking tasks are left to machines while humans are freed to invent new tasks to pay each other for with all the wealth that technological efficiencies have saved or created for them.

As amazing as the present is compared to the past, the future can be an even more extreme improvement. If AI proves powerful enough to continuously transform the macroeconomy as the fearmongers predict, and so do I, this will mean such massive productivity gains that machines will eventually be running the farms and factories at almost no cost. This will render necessities more and more affordable until almost every worker can engage in more niche artforms, services, and research areas than employ almost anyone full-time in today’s economy. In addition, whole new realms of technological possibility can be unlocked, in outer space, the Metaverse, and elsewhere.

It is hard to imagine ever reaching a logical conclusion of this process, at which artificial intelligence is better than human labor for literally every purpose. That would even involve convincing those who prefer some services to have a “human touch” for sentimental, aesthetic, philosophical, or spiritual reasons that human labor is unhelpful even to them. If AI does get that powerful, that will be an end of material scarcity in which everything is free and worrying about “unemployment” will make no sense at all.

Instead of worrying about that hypothetical utopia of widespread godlike agency and infinite abundance, let’s focus on reducing human drudgery and increasing material wealth by proliferating artificial intelligence and other technological progress in the here and now.

House Republicans are cautiously supportive of a bipartisan bill aimed at forcing the Department of Justice (DOJ) to release all its files on Jeffrey Epstein’s case after President Donald Trump gave the bill his stamp of approval on Sunday night.

GOP lawmakers who spoke with Fox News Digital Monday evening said they would vote for the bill and were optimistic their colleagues would as well — though many of them said they still had concerns about how it was written.

It comes after Speaker Mike Johnson, R-La., who had been against the bill but pushing parallel transparency efforts in Epstein’s case, said he hoped it would undergo material changes when it reached the Senate to give more protection for innocent people whose names may appear in the files against their wishes.

‘I have real concerns about the discharge language in the House draft,’ Johnson said. ‘But I do have some comfort that, I think if and when it’s processed in the Senate, that they’ll be able to correct some of those concerns, if we have the protection of victims and whistleblowers and all the rest.’

The legislation is coming to the House floor on Tuesday afternoon via a mechanism called a discharge petition led by Rep Ro. Khanna, D-Calif., and Rep. Thomas Massie, R-Ky. The latter has found himself at odds with both Johnson and Trump on several key issues this year.

A discharge petition allows a bill to get a House-wide vote against leaders’ wishes, provided the petition gets support from most lawmakers in the chamber — which in this case, it did last week.

Rep. Byron Donalds, R-Fla., a Trump ally who is running for governor in Florida, said he would vote for the bill but shared Johnson’s concerns.

‘Number one, Congress has never released criminal files ever in the history of Congress. Two, there are victims, and I know we’re supposed to be trying to do what we can to sanitize their names or cover their names or redact their names, but you know, that doesn’t mean it’s going to be foolproof,’ Donalds said.

‘You could have victims that don’t want to be released, be identified, and then they have to go relive this again. What about those women? What if those women have kids now? What if those women have husbands now and they don’t want to go through this? So I think there’s a reason why political bodies don’t release criminal files.’

Donalds said he would vote to release the files, however, to move past this chapter and help victims get closure.

‘It’s become such a huge distraction here on Capitol Hill. And I do want to see justice for those victims, if they were abused,’ he said.

Republican Study Committee Chairman August Pfluger, R-Fla., said, ‘I’m gonna vote in favor of it, but it’s not perfect, and there’s a lot of things that need to be addressed.’

‘Transparency is key. My district needs transparency. The president has nothing to hide, but things that need to be fixed, have to be fixed in the Senate,’ Pfluger, who pledged to support the bill before Trump’s blessing, said.

Rep. Erin Houchin, R-Ind., said she had similar concerns ‘from the start.’

‘Once it goes to the Senate, if the Senate believes they need to have broader or, you know, bigger protections, then I think that’ll be up to the Senate to decide, but I’m ready to vote this out of the House and send it over to the Senate and get moving on it,’ Houchin said.

A member of the conservative House Freedom Caucus, Rep. Andy Ogles, R-Tenn., questioned whether such a move by Congress could get in the way of the DOJ’s active probes into Epstein.

‘I have concerns as well. I mean, you have the Department of Justice investigations taking place. Are we inadvertently interfering?’ he posed.

Ogles said, however, that he believed most House Republicans like himself would back the bill.

‘With the president coming out in support of it, I think that sends a clear message that he’s not afraid of what’s in it, the Democrats should be,’ he said.

Rep. Rich McCormick, R-Ga., similarly said he believed Trump’s support alleviated some difficulties for Republicans.

‘I think it releases any angst they might have when we’re voting for it,’ McCormick said. ‘I think most people will vote for it, I don’t think it’s going to be a controversial bill at all.’

Houchin told Fox News Digital, ‘I think he moved the needle tremendously, just to say, you know, let’s have a vote on it and let’s stop talking about it.’

But Rep. Russell Fry, R-S.C., disagreed that Trump’s support had a significant effect on shifting the tide.

‘I mean, maybe a little bit, but I think people were largely there anyway,’ Fry said. ‘We talked about this on the campaign trail, The guy was a total dirtbag, did unspeakable atrocities on women in our country, and the public wants closure…this has been the most transparent Congress and administration on this subject in the country’s history.’

Trump posted on Truth Social on Sunday night, ‘House Republicans should vote to release the Epstein files, because we have nothing to hide, and it’s time to move on from this Democrat Hoax.’

It appeared to lead to Rep. Troy Nehls, R-Texas, who notably said he would oppose the measure on Friday, changing his mind as of Monday night. He told reporters ‘everybody’ would vote in favor of the bill and pointed out, ‘Donald Trump made a decision.’

House Oversight Committee Chairman James Comer, R-Ky., who was leading the Johnson-backed probe into Epstein, appeared similarly resigned on Monday.

‘At this point, I just think the best thing to do — there’s so much media frenzy and curiosity about this, and you know, the survivors act like they want everything to come out. I want everything to come out….any other villains in this, we’ll try to figure out what we can,’ he said.

And Massie told reporters that same evening that he would be open but cautious about any changes to his bill in the Senate.

‘If the Senate wants to improve this bill without limiting the disclosure, that would be fine by me. But if they try to monkey it up, I think those senators are gonna get in front of a freight train and be in a lot of trouble with their supporters,’ he warned.

Massie told Fox News Digital of Johnson’s concerns, ‘He needs to be for it or against it. I think he’s going to vote for it, so he must think there’s more good than bad.’

Senate Majority Leader John Thune, R-S.D., has not yet said what he would do if the bill passed the House on Tuesday.


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Rio Tinto (ASX:RIO,NYSE:RIO,LSE:RIO) said on Monday (November 17) that it has signed a joint development agreement with environmental technology company Calix (NYSE:CALX,ASX:CXL) to develop Calix’s Zero Emissions Steel Technology (Zesty) green iron demonstration plant in Western Australia.

If approved, the plant will be built at a site in Kwinana, south of Perth, that was previously earmarked for Rio Tinto’s BioIron research and development facility and associated pilot plant.

Under the deal with Calix, Rio Tinto will invest more than AU$35 million, pending project milestones. Funding from the mining giant will include both in-kind and financial contributions.

The plant received AU$44.9 million in Australian Renewable Energy Agency support in July.

Rio Tinto’s work will include helping Calix reach a final investment decision through technical support, engineering services and advocacy. Subject to a final investment decision and successful project construction, Rio Tinto will provide up to 10,000 tonnes of various Pilbara iron ores for plant commissioning and the initial testing phase.

The miner will also provide introductions to potential customers for downstream use of the Zesty product.

“The world needs low-emissions steel if it is going to decarbonise, and we continue to look at a range of ways Pilbara iron ores can help to do this as new technologies emerge,” said Rio Tinto Iron Ore Chief Executive Matthew Holcz.

He added that Rio Tinto will keep progressing BioIron with its partners, the University of Nottingham and Metso. However, the company has decided that the current furnace design requires additional development.

“Both projects are part of our work to reduce emissions and support the future of iron ore in Australia and the communities that depend on it,’ Holcz added, referring to Zesty and BioIron.

Securities Disclosure: I, Gabrielle de la Cruz, hold no direct investment interest in any company mentioned in this article.

This post appeared first on investingnews.com

East Star Resources (LSE:EST) and Endeavour Exploration announced they have entered into a binding earn-in and joint venture (JV) agreement to advance gold exploration in Kazakhstan.

Endeavour Exploration, a subsidiary of top gold producer Endeavour Mining (LSE:EDV,TSX:EDV,OTCQX:EDVMF), will have the right to earn up to an 80 percent interest in a new JV company via staged investments.

Stage 1 includes a US$5 million payment within two years, equivalent to a 51 percent interest. If an additional US$20 million is given over three years, its interest will increase to 70 percent.

The last 10 percent will be given to Endeavour if it funds and completes a prefeasibility study.

During the initial phase, East Star will act as manager of the JV.

The area of interest for the partnership includes two proven, underexplored mineral belts.

‘This agreement with Endeavour is a transformational milestone for East Star that validates the quality of our exploration programme and provides a clear pathway to unlock the full potential of our gold exploration strategy,” said East Star Resources CEO Alex Walker in a November 13 press release.

While the JV will focus on gold, East Star is also pursuing copper in Kazakhstan.

Its assets include a volcanogenic massive sulfide deposit with a JORC-compliant resource estimate of 20.3 million metric tons at 1.16 percent copper, 1.54 percent zinc and 0.27 percent lead.

An investor webcast is scheduled for Tuesday (November 18) to discuss the terms of the JV.

Both parties will fund the JV company in proportion to their ownership share after the earn-in period.

Securities Disclosure: I, Gabrielle de la Cruz, hold no direct investment interest in any company mentioned in this article.

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Silver mining companies are being supported by a silver price bull run in 2025.

After climbing through 2025, silver broke its all-time high set in 1980 this October, reaching a new high of US$54.47 per ounce on October 17.

The factors driving the metal’s rise remain, most notably tightening supply and demand fundamentals driven by higher demand from industrial sectors and its use in photovoltaics.

Additionally, prices have found tailwinds from safe-haven investors who find silver’s lower entry price compared to gold appealing. They have moved toward silver on the back of uncertainty in global financial markets as the US implements tariff policies, as well as escalating tensions in the Middle East and the unresolved conflict between Russia and Ukraine.

Below is an overview of the five largest silver-mining stocks by market cap as of November 10, 2025, as per TradingView’s stock screener. Read on to learn more about the activities and operations of these large-cap silver stocks.

1. Pan American Silver (TSX:PAAS,NYSE:PAAS)

Market cap: C$20.62 billion
Share price: C$52.51

Pan American Silver is among the world’s largest primary silver producers, with silver assets located throughout the Americas and operations in Peru, Mexico, Bolivia, Argentina and Chile. Its largest silver-producing asset is its wholly owned La Colorada mine in Mexico.

On May 11, Pan American entered into a definitive agreement to acquire all of the issued and outstanding shares of MAG Silver (TSX:MAG,NYSEAMERICAN:MAG). Under the terms of the US$2.1 billion deal, MAG shareholders will be paid out a mix of cash totaling US$500 million and 0.755 shares in Pan American per MAG share.

On September 4, Pan American announced the deal’s closing, giving it a 44 percent stake in the Juanicipio mine in Central Mexico. The mine is operated by Fresnillo (LSE:FRES), which holds the remaining 56 percent.

According to its Q3 report, released on November 12, the company’s attributable silver production during the period totaled 5.46 million ounces.

The La Colorada mine was the biggest contributor, producing 1.51 million ounces of silver during the quarter. Other significant contributions came from the El Peñon gold-silver mine in Chile with 938,000 ounces of silver, Huaron in Peru at 755,000 ounces, San Vicente in Bolivia at 765,000 ounces and Cerro Moro in Argentina at 559,000 ounces.

Additionally, its attributable silver production from its 44 percent stake in Juanicipio in Mexico totaled 580,000 ounces in the month of September alone.

Pan American Silver also upgraded its 2025 operating outlook to account for Juanicipio’s additional production, and now expects full-year attributable silver production between 22 million to 22.5 million ounces. The company also lowered its expected silver segment all-in sustaining costs to a range of US$14.50 to US$16.00 per ounce.

2. First Majestic Silver (TSX:AG,NYSE:AG)

Market cap: C$7.83 billion
Share price: C$16.61

First Majestic has three wholly owned silver-producing mines in Mexico: San Dimas in Durango, Santa Elena in Sonora and La Encantada in Coahuila. The first two also produce gold.

The company holds a 70 percent stake in the Los Gatos silver mine in Chihuahua as well. First Majestic acquired the property in January 2025 through a merger with Gatos Silver.

Japan’s Dowa Holdings (TSE:5714) holds the remaining 30 percent interest.

In addition to its producing assets, First Majestic sells bullion from its own minting facility in Nevada, US, named First Mint. It commenced sales in March 2024.

According to its Q3 report, the company achieved record quarterly production of 3.86 million ounces of silver, a 96 percent increase from the 1.97 million million ounces produced in the same period in 2024.

First Majestic’s recently acquired Los Gatos mine was its largest producer, delivering 1.41 million attributable ounces of silver. San Dimas took second place at 1.47 million ounces, while La Encantada and Santa Elena produced 575,193 ounces and 412,669 ounces, respectively.

3. Endeavour Silver (TSX:EDR,NYSE:EXK)

Market cap: C$2.93 billion
Share price: C$11.12

Endeavour Silver is a mining company with two operating silver-gold mines in Mexico — Guanaceví and Bolañitos — plus the commissioning-stage Terronera project and several exploration properties.

On May 1, the company completed the acquisition of Compañia Minera Kolpa and the Huachocolpa Uno mine in Peru for total consideration of US$145 million in a combination of cash and Endeavour shares to Kolpa shareholders.

Endeavour also agreed to pay an additional US$10 million in cash in contingent payments if certain events are met, and will add US$20 million in net debt, which will remain outstanding and repayable by Minera Kolpa.

In its Q3 production report, Endeavour reported silver production of 1.77 million ounces, 102 percent higher than the 874,717 ounces in the third quarter of 2024. A large portion of the increase was owed to the acquisition of Kolpa, which delivered 598,689 ounces of silver through Q3.

The company also provided an update on Terronera, which is nearing commercial production. Between September 1 and September 23, milling rates averaged 1,866 metric tons per day, with average silver recoveries of 82.8 percent. Additionally, the mine delivered 212,043 ounces of silver during the third quarter.

4. Silvercorp Metals (TSX:SVM)

Market cap: C$1.94 billion
Share price: C$9.58

Silvercorp Metals is a production and development company operating two silver mines in China: the Ying Mining District in Henan and the GC mine in Guangdong. It is also working to develop the copper primary El Domo project in Central Ecuador.

In the company’s operations report for its fiscal Q2 2026 ended September 30, it reported total silver production of 1.66 million ounces, a 0.2 percent increase from the same period last year. The majority of its output came from the Ying Mining District, which delivered 1.53 million ounces of silver, with the remaining 130,000 ounces coming from the GC mine.

In addition to mining activities, the company reported 77,507 meters of exploration drilling at Ying and 14,437 meters of tunnelling.

Silvercorp also reported that construction activities at El Domo had advanced during the quarter, with 1.29 million cubic meters of material removed from the site. Although the mine is being developed as a copper mine, it will also produce silver as a by-product metal.

The company’s environmental license for the project was the subject of a court challenge, but on August 5, Silvercorp announced that the Constitutional Court of Ecuador rejected the challenge in a unanimous decision.

5. Vizsla Silver (TSX:VZLA,NYSEAMERICAN:VZLA)

Market cap: C$1.9 billion
Share price: C$5.91

Vizsla Silver is advancing its Panuco silver-gold project in Sinaloa, Mexico, toward production.

It released an updated preliminary economic assessment for the Panuco project on February 20, suggesting a post tax net present value of US$1.14 billion with an internal rate of return of 85.7 percent and a pay back period of less than 1 year.

Measured and indicated silver resources at the site totaled 127.82 million ounces of contained silver from 12.96 million metric tons of ore with an average grade of 307 grams per metric ton (g/t) silver. Its inferred resource totals 73.62 million ounces of silver from 10.47 million MT of ore with an average grade of 219 g/t.

On June 18, Vizsla reported that it had advanced 125 meters at its Copala test mine and was progressing at a rate of 4 meters per day. Once development reaches the main deposit, Vizsla will take a 10,000 metric ton bulk sample. The portal will also serve as the primary access for underground mining operations once a construction decision is made.

Additionally, in May, the company entered into an agreement to acquire the producing Santa Fe silver-gold mine and property located to the south of Panuco. The property hosts operating mining infrastructure, including a processing plant and an underground mine built in 2018. Between 2020 and 2024, the mine processed 370,366 metric tons of ore, with an average head grade of 203 g/t silver and 2.17 g/t gold.

Under the terms of the agreement, Vizsla will have the option to acquire a 100 percent interest in the Santa Fe producing concessions for US$4 million in exploration expenditures, along with cash considerations of US$1.5 million and 1.37 million Vizsla shares over five years. It also entered a purchase agreement to buy the Santa Fe exploration concessions for a further US$1.43 million and 2.75 million common shares.

On September 5, Vizsla executed a mandate letter for up to US$220 million toward the development of the Panuco project. While the deal isn’t expected to close until Q1 2026, Vizsla will be able to draw an initial tranche of US$25 million for immediate funding of early development and construction preparation.

FAQs for silver investing

Is silver a good investment?

Silver comes with many of the same advantages as its sister metal gold. Both are considered safe-haven assets, as they can offer a hedge against market downturns, a weakening US dollar and inflation.

Additionally, many investors like being able to physically own an asset, and with its lower price point, buying silver coins and bars is an accessible option for building a precious metals portfolio. Of course, physical silver isn’t the only way to invest in the metal — there are also silver stocks and various silver exchange-traded funds.

It’s up to investors to do their due diligence and decide whether silver is the right match for their portfolio.

Does silver go up when the stock market goes down?

Historically, silver has shown some correlation with stock market moves, although it’s not consistent. When the stock market has seen its worst crashes, silver has moved down, but by a less significant amount than the stock market has, showing that it can act as a safety net to lessen losses in tough circumstances.

However, silver is also known for its volatility. What’s more, because it has industrial applications as well as a currency side, silver is less tied to the stock market than gold is.

Securities Disclosure: I, Dean Belder, own shares of Vizsla Silver.

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Researchers have documented the first known recovery of naturally formed nanoscale monazite from a living plant, potentially opening up new paths to recover in-demand rare earth materials.

The study, published this month in Environmental Science & Technology, identifies nanoscale monazite crystals inside Blechnum orientale, an evergreen fern known to accumulate rare earths at unusually high concentrations.

The work was carried out by researchers at the Guangzhou Institute of Geochemistry under the Chinese Academy of Sciences, in collaboration with a geoscientist at Virginia Tech in the US.

In the paper, the authors write that the discovery “opens new possibilities for the direct recovery of functional rare earth element (REE) materials,” adding, “To our knowledge, this is the earliest reported occurrence of rare earth elements crystallising into a mineral phase within a hyperaccumulator.”

The method, known as phytomining, relies on certain plants that naturally pull unusual amounts of metals from the ground. In this case, the fern absorbed rare earths so efficiently that tiny mineral crystals formed inside its tissues.

The mineral identified — monazite — is normally created deep underground under intense heat and pressure.

The team’s analysis shows that the fern somehow produced nanoscale versions of it under normal surface conditions, with the highest concentrations found in its leaflets and roots. In this state, the plant appears to lock the metals outside its cells as a way of protecting itself, with the process enabling the mineral to crystallize.

Monazite is prized for uses ranging from lasers to electronics to materials that withstand high heat and radiation, so finding it naturally produced inside a plant could open up a new, lower-impact source of rare earths.

REEs take priority in global supply race

REEs, a group of metals used in permanent magnets, lasers, consumer electronics and advanced defense systems, are receiving renewed international scrutiny as governments race to reduce dependence on concentrated supply chains.

Earlier this month, the US Department of the Interior published its final 2025 list of critical minerals, naming 60 minerals deemed vital to the American economy and exposed to supply risk.

The list emphasizes the importance of rare earths, which the US imports heavily, and highlights neodymium, scandium and dysprosium as metals where supply disruptions would impose the “highest cost” on the US economy.

Washington has moved in parallel to strengthen access to rare earths through domestic production, expanded mapping of US deposits and agreements with partners in Australia, Japan, Malaysia and Thailand.

In addition to these efforts, US officials continue to signal confidence that Beijing will adhere to commitments under a rare earths framework outlined last month.

Secretary of the Treasury Scott Bessent said in a recent interview that a deal with China will “hopefully” be done by Thanksgiving, while also rejecting a report suggesting that Beijing is planning new restrictions on US companies.

Are plants a viable source of rare earths?

The use of ferns for mineral extraction remains at an early stage, and the researchers emphasize that phytomining is not a replacement for conventional production.

But finding mineralized rare earths in a living organism offers a proof of concept that could broaden how countries approach resource development at a time when REEs remain strategically critical for major economies.

As the US, China and other nations look for secure supply routes, the possibility that plants themselves may contribute to the pipeline adds a new dimension to a field dominated by mining companies.

Securities Disclosure: I, Giann Liguid, hold no direct investment interest in any company mentioned in this article.

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Graphite One (TSXV:GPH,OTCQX:GPHOF) announced on November 13 that it has identified rare earth elements (REEs) at its Graphite Creek deposit, located north of Nome, Alaska.

“The presence of two Defense Production Act Title III materials — graphite and REEs — in a single deposit further underscores Graphite Creek’s position as a truly generational deposit,” said President Anthony Houston.

“Given the robust economics of our planned complete graphite materials supply chain, the presence of Rare Earths at Graphite Creek suggests that recovery as a by-product to our graphite production will maximize the value.”

Geochemical analysis of drillcore samples reveals elevated levels of heavy rare earths and all five principal permanent magnet REEs: neodymium, praseodymium, dysprosium, terbium and samarium.

Testwork is ongoing at the University of Alaska Fairbanks’ Advanced Instrumentation Laboratory, and at Activation Laboratories. Graphite One is also collaborating with a US Department of Energy national lab on REE extraction.

REEs are essential to modern technologies, from permanent magnets in wind turbines and electric vehicles, to high-performance fiber optics, lasers and defense systems.

China, which dominates global production of both magnet REEs and graphite, imposed export limits last year and has continued to expand these restrictions in 2025.

Graphite One is advancing a US-based graphite supply chain, including transport from Nome to an advanced graphite and battery materials plant in Warren, Ohio, with a co-located recycling facility to reclaim graphite and other materials.

Graphite Creek has received support through a US$37.5 million Defense Production Act Title III grant, as well as non-binding letters of interest totaling US$895 million from EXIM Bank.

Securities Disclosure: I, Giann Liguid, hold no direct investment interest in any company mentioned in this article.

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