1. San Lorenzo Gold (TSXV:SLG)

Year-to-date gain: 641.18 percent
Market cap: C$55.06 million
Share price: C$0.80

San Lorenzo Gold is an exploration company working to advance its Salvadora project in the Chañaral province of Chile. The property consists of 25 exploration and nine exploitation concessions covering an area of 8,796 hectares, and hosts a large copper and gold porphyry system with several significant targets.

According to the project page, the site geology resembles that of the nearby Codelco-owned Salvador copper mine, which has operated since the early 1950s and is expected to continue until the mid-2060s following an expansion.

San Lorenzo’s share price gained significantly in the first quarter starting on March 3, when the company announced a significant discovery hole, the first of three holes drilled at Salvadora’s Cerro Blanco gold-copper target.

The discovery hole demonstrated an average grade of 1.04 grams per metric ton (g/t) gold over a broad 153.5 meters starting at a depth of 229 meters, including an intersection grading 12.78 g/t gold over 3.8 meters.

The same day, it also released partial results for the first of three holes drilled at its Arco de Oro gold target. They returned multiple instances of high-grade gold, including 5.61 g/t gold over 6.6 meters at a depth of 15.7 meters and 4.8 g/t gold over 23.3 meters 174.4 meters from surface.

Assays for the remaining holes were released in mid-March and April, respectively. San Lorenzo released the most recent results from exploration on August 6, reporting that an induced polarization geophysical survey at Salvadora identified multiple prospective anomalies that would be the focus of its upcoming drill program.

San Lorenzo announced on September 24 that it initiated the aforementioned drill program, with plans in place for a minimum of three holes at Cerro Blanco and four holes at Arco de Oro.

After leveling out in Q2, company shares began gaining momentum in early August, largely continuing to move through the rest of Q3 and into Q4. Shares of San Lorenzo jumped to a year-to-date high of C$0.86 on October 23.

2. Prospector Metals (TSXV:PPP)

Year-to-date gain: 833.31 percent
Market cap: C$129.56 million
Share price: C$1.12

Prospector Metals is exploring its flagship ML gold project near Dawson City in Yukon, Canada.

The 10,869 hectare property is located within the Tintina Gold Belt, which hosts significant historic mining operations and current exploration and development projects. The ML project’s Skarn Ridge and North Vein targets were the focus of significant historical work through 2008, including 117 diamond drill holes. According to Prospector, historical work also led to the discovery of more than two dozen untested high-grade gold surface occurrences.

A maiden drill program at the site commenced on June 23, with the primary focus on the Bueno target, which delivered rock samples with grades up to 156 g/t during May 2025 exploration. The program will include testing of six targets, including Bueno, identified during the company’s 2024 exploration program.

After trending upwards throughout the year from their start of C$0.12, shares of Prospector surged from C$0.31 to C$1.17 when it reported the discovery of the new TESS gold-copper zone on October 1. The company reported a drill hole intersected the broad, high-grade zone, with an average grade of 13.79 g/t gold from 62 meters to 106 meters downhole, including 288 g/t over 1 meter within 21.93 g/t over 24.65 meters. The hole also intersected the North Vein zone from 138 meters to 145.36 meters downhole, over which it had an average grade of 5.69 g/t gold.

Prospector CEO Rob Carpenter said, “The discovery represents an exciting new style of gold mineralization for the ML project. The high-grade and near surface intercept occurs within a distinct zone that is coincident with a diagnostic surface geochemical signature.” He indicated that the company has traced the trend on the surface for at least 500 meters.

Shares of Prospector reached a year-to-date high of C$1.30 the following day.

On November 26, Prospector reported the final assays from its drill program, including an interval at the TESS Zone grading 7.29 g/t gold and 0.91 percent copper over 14 meters, as well as one in the Skarn Ridge Zone that graded 2.04 g/t gold and 0.42 percent copper over 27 meters. Carpenter said the company is planning a fully funded drill program to extend the zones along trend and test new targets.

3. PPX Mining (TSXV:PPX)

Year-to-date gain: 785.71 percent
Market cap: C$219.63 million
Share price: C$0.31

PPX Mining is a precious metals company that is focused on its Igor project, which contains the operating Callanquitas underground mine, located in the Otuzco province of Northern Peru.

An updated resource estimate for Callanquitas released by the company in January 2024 showed a measured and indicated oxide resource of 81,090 ounces of gold and 2.9 million ounces of silver. The inferred resource as sulfides stands at 34,450 gold equivalent ounces from ore grading 4.63 g/t gold equivalent.

According to a prefeasibility study for Igor amended in January 2022, the 1,300 hectare site previously hosted small-scale mining operations and holds a 50 MT per day gold-processing plant from the 1980s.

In November 2024, PPX started construction of a 350 metric ton per day carbon-in-leach and flotation plant that will be used to process oxide and sulfide ore from Callanquitas.

The latest construction update came on September 24, when the company said development was continuing at an accelerated pace while it worked on parallel activities. These advancements included the installation of leach tanks and the assembly of the crushing line. In all, the PPX reported that construction was 55 percent complete.

Meanwhile, exploration at Callanquitas carried on during the third quarter, with PPX reporting assay results on August 20. In that release, the company said it had encountered a highlighted grade of 3.55 g/t gold over 4.2 meters, which included an intersection of 5.16 g/t gold over 2 meters.

Additionally, PPX announced on September 11 that it had closed an upsized non-brokered private placement for gross proceeds of C$2.58 million, which will be used for ongoing exploration at Callanquitas.

The following month, the company announced a binding letter of intent with Glencore (LSE:GLEN,OTC Pink:GLCNF) for a strategic investment, offtake agreement and technical collaboration, which it closed in December.

The investment results in gross proceeds of C$19.92 million for PPX, which will be used to advance a variety of work at the project, including the construction, commissioning and start-up of the plant. Additionally, under the agreement, Glencore has the right to acquire 100 percent of precious metals concentrate from the Igor project and plant beginning once the plant is commissioned.

Shares of PPX Mining reached a year-to-date high of C$0.48 on October 8.

4. Pelangio Exploration (TSXV:PX)

Year-to-date gain: 728.57 percent
Market cap: C$56.03 million
Share price: C$0.29

Pelangio Exploration is a gold exploration company with projects in Ghana and Canada. In Ghana, it owns two large-scale gold projects, the Manfo property and the Obuasi property. The latter is located 4 kilometers along strike and adjacent to AngloGold Ashanti’s (NYSE:AU,JSE:ANG) high-grade Obuasi mine.

Much of Pelangio’s market moving news came in the second half of the year.

In July, the company kicked off a high-resolution aeromagnetic drone survey at its Manfo and Nkosuo deposits. The following month, Pelangio announced the completion of an updated mineral resource estimate for Manfo covering four gold deposits, including the Nkasu deposit, which was not included in the maiden resource estimate.

The updated resource shows a total indicated mineral resource of 441,000 ounces of gold at an average grade of 1.16 g/t gold, up 126 percent from the maiden resource estimate, and a total inferred mineral resource of 396,000 ounces of gold at an average grade of 0.77 g/t gold, up 395 percent.

In September, Pelangio shared its plans for a US$7.6 million staged exploration program including up to 45,000 meters of drilling. Then, on October 22, the company closed the last tranche of a non-brokered private placement for gross proceeds of C$4.5 million.

Shares of Pelangio reached a year-to-date high of C$0.29 on December 1.

5. Kirkland Lake Discoveries (TSXV:KLDC)

Year-to-date gain: 650 percent
Market cap: C$49.97 million
Share price: C$0.30

Kirkland Lake Discoveries is a gold and copper exploration company focused on projects in its district-scale land package located in the Kirkland Lake area of Ontario, Canada.

Its holdings span an area of approximately 38,000 hectares in the Abitibi Greenstone Belt and are broadly divided into KL West and KL East, which contain the Goodfish-Kirana and Lucky Strike gold projects, respectively, among others.

On April 29, the company expanded KL West’s southern portion by entering into a mining option agreement with Val-d’Or Mining (TSXV:VZZ) to acquire a 100 percent interest in the Winnie Lake and Amikougami properties, and mining claim purchase agreements with two vendors for further claims around the Winnie Lake Pluton.

On August 6, Kirkland Lake initiated the inaugural diamond drill program at the site, designed to follow up on historic drill results and recent surface exploration. Early results from the program came on August 12 when the company reported the discovery of an intrusion-related system at KL West’s Winnie showing.

Next, on August 26, Kirkland expanded the mineralized system after intersecting semi-massive and massive sulfide mineralization across three additional holes at KL West, with assay results pending.

On September 23, Kirkland Lake announced a C$7 million private placement with a significant portion coming from investors Eric Sprott, Rob McEwen and Crescat Capital. It had been upsized to C$14 million as of October 3.

Drilling at KL West resulted in a new gold discovery 2 kilometers northeast of the Winnie Shaft, the company reported on October 27, which Kirkland says is an intrusive-related mineralizing system centered on the Winnie Pluton with a 17 kilometer perimeter. The testing confirmed a distinct and coexisting copper-rich massive sulfide system as well.

In late November, Kirkland commenced a fully funded 25,000 diamond drill program focused on KL West and ‘surrounding structures associate with the Winnie Lake Stock.’

Shares of Kirkland Lake reached a year-to-date high of C$0.39 on October 28.

Investor Insight

Sankamap Metals offers exposure to new copper–gold discovery potential in one of the last underexplored regions of the Ring of Fire, with two fully owned, drill-ready assets positioned along a world-class mineral belt.

Company Highlights

• Two 100 percent owned copper and gold properties – Kuma and Fauro – within a highly prospective copper-gold trend in the Solomon Islands.
• Drill-ready targets supported by strong historical sampling, including grab samples up to 11.7 percent copper, 13.5 grams per ton (g/t) gold at Kuma, and 173 g/t gold; plus, drill intercepts of 35 m at 2.08 g/t gold at Fauro.
• Strategically located along the same mineral belt as major deposits, including Newmont’s 71.9 Moz Lihir gold mine.
• Underexplored mining-friendly jurisdiction with strong government support and established local workforce.
• Large-scale system potential, including a km-scale copper-gold anomaly at Kuma and multiple high-grade epithermal and porphyry-style targets at Fauro.
• Inaugural drilling at Kuma, scheduled to begin in January 2026, marking a major catalyst for the project.
• Strong technical leadership, with a management team that has collectively raised over $1 billion and delivered significant shareholder returns.

Overview

Sankamap Metals (CSE:SCU) is a Canadian exploration company advancing the Oceania Project, a high-impact copper–gold opportunity in the mineral-rich South Pacific. The project includes two fully permitted properties – Kuma and Fauro – in the Solomon Islands, one of the last untapped frontiers of the Pacific Ring of Fire.

The company’s land package is strategically positioned near world-class deposits, such as Newmont Mining’s 71.9 Moz Lihir gold mine and Bougainville Copper’s historic Panguna deposit with 19.3 Moz gold and 5.3 Mt copper resources.

CEO John Florek investigating mineralized outcrop at Kuma property during the summer site visit

Kuma and Fauro are 100 percent owned and drill-ready. Both assets benefit from compelling historical sampling, large-scale geophysical anomalies, and district-scale geological characteristics that support the potential for major porphyry and epithermal systems.

The company focuses on systematic exploration, delineating high-priority drill targets to unlock discovery opportunities. With strong national support for mining and a leadership team deeply experienced in major global jurisdictions, Sankamap is well positioned to generate early and meaningful shareholder value as exploration advances.

Key Properties

Kuma Property

The Kuma property spans 43 sq km and lies 37 km southeast of Honiara on Guadalcanal Island. The property is considered a highly compelling drill-ready porphyry target. Historical sampling returned values up to 11.7 percent copper and 13.5 g/t gold, accompanied by a kilometre-scale copper-gold geochemical anomaly. Airborne geophysical surveys, including mobile magnetotelluric (MT), reveal resistive and conductive features consistent with porphyry, epithermal and skarn-style mineral systems.

Kuma benefits from year-round access and proximity to the Gold Ridge mine. Lidar, surface geochemistry, and geophysics surveys have advanced target definition toward a 2026 drill program. Alteration mapping defined a 2 km lithocap, indicating a potential significant porphyry below that’s not yet tested by drilling.

Kuma is positioned for discovery potential on a scale comparable to other major systems in the region.

Current work at Kuma is focused on refining priority drill targets through ongoing analysis of newly released geophysical and geological datasets. A field visit in November was aimed at ground-truthing these targets, confirming interpretations, and finalizing on-the-ground logistics. Pad and camp construction began in late November, ahead of the inaugural drilling campaign set for January 2026, an important milestone in advancing the Kuma property toward discovery.

Fauro Property

The 147 sq km Fauro property encompasses a high-grade epithermal gold target with indications of a porphyry system at depth. Formed by the collapse of the Fauro calc-alkaline volcano, the property hosts seven prospects, three of which are drill-ready. Historical results include a grab sample of 173 g/t gold, trench results of 8 m at 27.95 g/t gold, and drilling intercepts such as 35 m at 2.08 g/t gold. Multiple zones, including Meriguna, Ballyorlo and Kiovakase, exhibit robust soil anomalies and magnetic highs, underscoring the property’s potential to host a large-scale deposit comparable in setting to the Lihir gold system.

Since 2024, new sampling has confirmed continued high-grade potential, with assays returning up to 19.25 g/t gold and up to 4 percent copper, expanding evidence for a hybrid epithermal-porphyry system. With year-round drilling access and efficient transport via helicopter and boat, Fauro represents a major exploration opportunity with multiple existing gold intercepts and untested porphyry indicators.

Management Team

John Florek – Chief Executive Officer

John Florek has more than 35 years of experience with major and junior mining companies, including BHP, Placer Dome, Barrick, Teck, and Detour Gold/Kirkland Lake Gold/Agnico Eagle. He has identified and advanced significant mining assets from early exploration through development and currently sits on the board of McEwen Mining. He is also CEO, president and director of Emperor Metals.

John Williamson – Chairman, Co-founder and Director

A professional geologist with more than 35 years in the global mining sector, John Williamson founded more than 20 successful companies and the Metals Group. He has raised more than $1 billion across public and private markets, delivering strong returns to shareholders.

Sean Mager – CFO and Director

With 30+ years in the global mining sector, Sean Mager brings extensive experience in corporate development, stakeholder relations, regulatory affairs, finance and operations. He is a co-founder of the Metals Group.

Krystle Adair – Vice-president, Exploration

A geologist with more than 13 years of exploration experience across the Americas, Krystle Adair has managed projects across multiple deposit types. She has worked extensively with Metals Group companies and is a registered professional geoscientist in British Columbia.

Hannett – Director

A Bougainville Island national and professional engineer with 17+ years of experience, Arthur Hannett has worked with major operators including Placer Dome, Barrick, Glencore and Agnico Eagle.

Donald Marahare – Director

A seasoned legal professional with 20+ years of experience in the Solomon Islands, Donald Marahare is the principal at DNS & Partners Law Firm, admitted to the High Court in 2000. He also serves as president of the Solomon Islands Football Federation.

U3O8 spot price, December 5, 2024, to December 5, 2025.

Chart via Trading Economics.

Despite a subdued stretch for the price, uranium’s long-term drivers remain firmly intact, and arguably have only improved over the course of the year. Combined with renewed investor appetite, that strength has helped lift uranium equities throughout 2025, reinforcing confidence in the sector’s long-term thesis.

Uranium investment demand surges

For Joe Kelly, CEO of Uranium Markets, one of the most compelling uranium market trends in 2025 was the growth in investor demand, particularly for physical uranium.

SPUT had added 7.8 million pounds, growing its uranium holdings to 74.04 million pounds, as of December 2, a 12 percent increase from 2024’s tally. Its net asset value had increased to US$5.68 billion.

Kelly explained that SPUT’s momentum was the result of broader investor enthusiasm, allowing the trust to purchase millions of pounds from the spot market, which “drove the price considerably higher.”

That dynamic extended beyond institutional vehicles.

“You also had investors buying uranium directly because they thought it was cheap and a good investment,” he said.

The result was a layer of financial demand on top of utility needs. According to Kelly, this speculative interest created demand outside of the nuclear power plants in the world. “That drove the price up a little bit higher than it would have been otherwise, without that enthusiasm from the investing community,” he added.

SPUT’s aggressive accumulation has become a clear market signal.

The trust’s growing holdings highlight how institutional investors increasingly view uranium as scarce, tightening available supply by removing material from the open market. As inventories shrink, upward pressure on prices builds.

At the same time, SPUT’s rising net asset value reflects renewed investor confidence tied to reactor buildouts, energy security priorities and the broader clean energy shift.

If the trust keeps buying while mine output lags and utilities lock in long-term contracts, the market could be moving toward a structural deficit, drawing even more attention to uranium equities and physical vehicles.

Uranium term price underscores market momentum

Often described as a more accurate barometer of market activity and sentiment, the long-term contract price displayed less volatility in 2025, starting the 12 month period at US$80 and reaching US$86 at the end of November.

Tiggre stressed that the uranium sector’s “real market is the long-term contract price,” not the day-to-day noise of the spot price. Long-term contracting, he said, is where “actual buyers, sellers, users and suppliers” negotiate prices that determine what it really takes to bring new pounds to market.

The challenge, however, is opacity. “It’s not transparent … they don’t disclose individual contracts,” he said. That leaves analysts to piece together trends from quarterly averages.

Long-term contract price, January 1 to November 30, 2025.

Chart via Cameco.

That underlying market has continued to strengthen from 2024 to 2025.

As Tiggre noted, the long-term price has been “going up, pausing, consolidating, going up,” reaching levels that “clearly do incent production” — yet even the world’s biggest producers have struggled to deliver.

Global uranium majors Cameco (TSX:CCO,NYSE:CCJ) and Kazatomprom “both failed to hit their targets and have officially moved their goal posts,” a signal he called “significant and … bullish.”

Meanwhile, would-be junior producers have not stepped in to fill the gap.

“None of them have been able to say, ‘Yeah, we’re going to build this or rehabilitate that’ and deliver on time,” he noted. What looked like low-hanging fruit has proven “thorny,” reinforcing that supply remains constrained.

At the same time, demand momentum has only accelerated. Headlines showcasing new reactor builds are now “weekly,” Tiggre said, with BRICS nations expanding aggressively and western governments shifting decisively pro-nuclear. Even in the US, he noted, “Trump has doubled down … he’s strongly pro-nuclear.”

The result: A structurally tight market where volatile spot moves obscure a far more durable trend.

“The fundamentals are just super strong,” Tiggre said. “I’m very bullish.”

Uranium doubles as a tech play

Part of uranium’s demand story is tied to forecast growth in artificial intelligence (AI) data center deployment, a segment where electricity consumption has grown by 12 percent since 2019, as per the International Energy Agency (IEA).

Currently data centers use 415 terawatt hours (TWh), representing 1.5 percent of global electricity demand, and that number is projected to increase rapidly over the next five years.

“Our Base Case finds that global electricity consumption for data centres is projected to double to reach around 945 TWh by 2030 in the Base Case, representing just under 3 percent of total global electricity consumption in 2030,” the IEA’s Energy Demand from AI report reads. “From 2024 to 2030, data centre electricity consumption grows by around 15 percent per year, more than four times faster than the growth of total electricity consumption from all other sectors.”

For Gerardo Del Real, publisher at Digest Publishing, the uranium sector’s momentum has shifted as an unexpected coalition of “tech bros” and “mining bros” reshapes the narrative around nuclear power.

“Who would have thought?” said Del Real, noting that after an 18 month stretch where the uranium trade “seemed stuck in the mud,” sentiment turned sharply once markets began viewing nuclear as a technology story.

“The market is one part fundamentals and the other part psychology,” Del Real explained, adding that the psychological boost from the booming tech sector has been powerful.

While he’s skeptical that every AI-fueled data center proposal will materialize, Del Real argued that even limited progress could supercharge energy demand. If tech companies “fulfill 35 percent to 50 percent of their promises,” he said, the resulting power requirements would be “absolutely spectacular.”

This comes as the uranium market was already heading toward a significant deficit by 2026, a trend Del Real believes has now accelerated. Leaning into his contrarian instincts, he said he has written “more checks than ever” for early stage uranium companies with trusted management teams.

“I am thrilled with the results thus far,” said Del Real.

“I think 2026 is going to be an inflection year where the breakout is really pronounced across the board.”

1. ProShares Ultra NASDAQ Biotechnology ETF (NASDAQ:BIB)

AUM: US$86.84 million

The ProShares Ultra NASDAQ Biotechnology ETF, launched in April 2010, is leveraged to offer twice daily long exposure to the broad-based NASDAQ Biotechnology Index, making it an ideal choice “for investors with a bullish short-term outlook for biotechnology or pharmaceutical companies.” However, analysts also advise investors with a low risk tolerance or a buy-and-hold strategy against investing in this fund due to its unique nature.

Of the about 250 holdings in this ETF, the top biotech stocks are Amgen (NASDAQ:AMGN) at 5.33 percent weight, Vertex Pharmaceuticals (NASDAQ:VRTX) at 5.27 percent and Gilead Sciences (NASDAQ:GILD) at 4.89 percent.

2. Direxion Daily S&P Biotech Bear 3x Shares (ARCA:LABD)

AUM: US$80.92 million

The Direxion Daily S&P Biotech Bear 3X Shares is designed to provide three times the daily return of the inverse of the S&P Biotechnology Select Industry Index, meaning that the ETF rises in value when the index falls and falls in value when the index rises.

Leveraged inverse ETFs are designed for short-term trading and are not suitable for holding long-term. They also carry a high degree of risk as they can be significantly affected by market volatility.

Unlike the other ETFs on this list, LABD achieves its investment objective through holding financial contracts such as futures rather than holding individual stocks.

3. Global X Genomics & Biotechnology ETF (NASDAQ:GNOM)

AUM: US$52.9 million

The Global X Genomics & Biotechnology ETF tracks the Solactive Genomics Index, focusing on companies involved in gene editing, genomic sequencing, genetic medicine, computational genomics and biotech.

The ETF holds 48 stocks, with about 90 percent in the pharmaceuticals, biotechnology and life sciences sector. Its top three holdings are Arrowhead Pharmaceuticals (NASDAQ:ARWR) at 6.06 percent, Guardant Health (NASDAQ:GH) at 5.5 percent and Illumina (NASDAQ:ILMN) at 5.05 percent.

4. Tema Heart and Health ETF (NASDAQ:HRTS)

AUM: US$52.53 million

Launched in November 2023, the Tema Heart and Health ETF tracks biotech stocks with a focus on diabetes, obesity and cardiovascular diseases. The fund was renamed on March 25 from Tema Cardiovascular and Metabolic ETF, and again on June 27 from the GLP-1 Obesity and Cardiometabolic ETF.

There are 47 holdings in this biotechnology fund, with about 75 percent being large-cap stocks and 22 percent mid-cap. About three-quarters of its holdings are based in the US. Its top biotech holdings are Eli Lilly and Company (NYSE:LLY) at a 10.25 percent weight, Roche Holding (OTCQX:RHHBY,SWX:ROG) at a 4.54 percent weight and UnitedHealth Group (NYSE:UNH) at a 4.25 percent weight.

5. Virtus LifeSci Biotech Products ETF (ARCA:BBP)

AUM: US$31.42 million

The Virtus LifeSci Biotech Products ETF tracks the LifeSci Biotechnology Products Index, focusing on US-listed biotech companies with at least one FDA-approved drug therapy.

Launched in December 2014 by Virtus Investment Partners, it provides targeted exposure to firms in the product stage, from startups to large players, through passive, equal-weighted holdings rebalanced semi-annually.

Its top holdings include Travere Therapeutics (NASDAQ:TVTX) at a weight of 3.32 percent, Ionis Pharmaceuticals (NASDAQ:IONS) at 3.22 percent and Insmed (NASDAQ:INSM) at 2.97 percent.